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    Rabbit Anti-RBM17/PE-Cy3 Conjugated antibody (bs-19765R-PE-Cy3)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-19765R-PE-Cy3
    英文名稱(chēng) Rabbit Anti-RBM17/PE-Cy3 Conjugated antibody
    中文名稱(chēng) PE-Cy3標記的RNA結合蛋白17抗體
    別    名 45 kDa-splicing factor; RBM 17; Rbm17; RNA binding motif protein 17; RNA binding motif protein17; RNA-binding motif protein 17; SPF 45; SPF45; SPF45_HUMAN; Splicing factor (45 kD); Splicing factor (45kD); Splicing factor 45; Splicing factor 45 kDa; Splicing factor 45kDa.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  結合蛋白  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Mouse,  (predicted: Human, Rat, Dog, Rabbit, )
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 45kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human RBM17
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009]

    Function:
    Splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia.

    Subcellular Location:
    Nucleus.

    Similarity:
    Contains 1 G-patch domain.
    Contains 1 RRM (RNA recognition motif) domain.

    Database links:

    Entrez Gene: 84991 Human

    Entrez Gene: 76938 Mouse

    Entrez Gene: 291295 Rat

    Omim: 606935 Human

    SwissProt: Q96I25 Human

    SwissProt: Q8JZX4 Mouse

    Unigene: 498548 Human

    Unigene: 182769 Mouse

    Unigene: 20694 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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