產(chǎn)品編號 | bs-17353R-Gold |
英文名稱(chēng) | Rabbit Anti-Homez/Gold Conjugated antibody |
中文名稱(chēng) | 膠體金標記的同源盒亮氨酸拉鏈蛋白HOMEZ抗體 |
別 名 | Homeobox and leucine zipper protein Homez; Homeodomain leucine zipper containing factor; KIAA1443. |
規格價(jià)格 | 100ul/2980元 購買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細胞生物 結合蛋白 鋅指蛋白 表觀(guān)遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應 | Mouse, (predicted: Human, ) |
產(chǎn)品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 60kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Homez |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Homeodomain-containing proteins function as transcription factors that typically switch on cascades of other genes. Usually homeodomain proteins act in the promoter region of their target genes as complexes with other transcription factors, leading to much higher target specificity than a single homeodomain protein. HOMEZ (Homeobox and leucine zipper protein) is a 525 amino acid nuclear protein that contains 3 atypical homeodomains, 2 leucine zipper-like motifs, proline and serine-rich motifs and an acidic domain. Within homeodomain 2, it contains a putative nuclear localization signal. HOMEZ shares significant sequence similarity with mouse ZHX1 and sequences that are homologous to HOMEZ are restricted to vertebrates. Likely functioning as a transcription regulator, HOMEZ is ubiquitously expressed with highest levels found in in ovary, testis, kidney, fetal lung and kidney. Function: Homez and members of ZHX family of zinc finger homeodomain factors are delineated as a subset within the superfamily of homeobox-containing proteins. Subcellular Location: Nuclear Database links: Entrez Gene: 57594 Human Entrez Gene: 239099 Mouse Omim: 608119 Human SwissProt: Q8IX15 Human SwissProt: Q504Z8 Mouse SwissProt: Q80W88 Mouse Unigene: 52743 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |