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    Rabbit Anti-GTF3A/Cy7 Conjugated antibody (bs-16357R-Cy7)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-16357R-Cy7
    英文名稱(chēng) Rabbit Anti-GTF3A/Cy7 Conjugated antibody
    中文名稱(chēng) Cy7標記的通用轉錄因子3A
    別    名 AP 2; AP2; Factor A; General transcription factor 3A; General transcription factor IIIA; GTF 3A; GTF3A; TF3A_HUMAN; TFIIIA; Transcription factor 3A; Transcription factor IIIA.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 轉錄調節因子  鋅指蛋白  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, )
    產(chǎn)品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 41kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GTF3A
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]

    Function:
    Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes.

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Ubiquitous.

    Similarity:
    Contains 9 C2H2-type zinc fingers.

    Database links:

    Entrez Gene: 2971 Human

    Entrez Gene: 66596 Mouse

    Entrez Gene: 246299 Rat

    Omim: 600860 Human

    SwissProt: Q92664 Human

    SwissProt: Q8VHT7 Mouse

    SwissProt: Q8VHT8 Rat

    Unigene: 445977 Human

    Unigene: 358698 Mouse

    Unigene: 195324 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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