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    Rabbit Anti-NIF1/Cy7 Conjugated antibody (bs-19246R-Cy7)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-19246R-Cy7
    英文名稱(chēng) Rabbit Anti-NIF1/Cy7 Conjugated antibody
    中文名稱(chēng) Cy7標記的鋅指蛋白335抗體
    別    名 1810045J01Rik; bA465L10.2; FZF-1; MGC86001; NIF-1; NIF-2; NIF2; NIF2, INCLUDED; NRC interacting factor 1; NRC-interacting factor 1; NRC-INTERACTING FACTOR; Nuclear Receptor Coactivator Interacting Factor 1; OTTHUMP00000031195; Zinc finger protein 335; Zinc finger/leucine zipper co transducer NIF1; zinc-finger/leucine-zipper co-transducer NIF1; ZNF335.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 轉錄調節因子  鋅指蛋白  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
    產(chǎn)品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 145kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NIF1
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure. [provided by RefSeq, Jul 2008]

    Function:
    Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.

    Subcellular Location:
    Nuclear

    Tissue Specificity:
    Expression is restricted to non-neuronal tissues.

    Database links:

    Entrez Gene: 535476 Cow

    Entrez Gene: 485904 Dog

    Entrez Gene: 63925 Human

    Omim: 610827 Human

    SwissProt: Q9H4Z2 Human

    Unigene: 174193 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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