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    Rabbit Anti-HOXB6/AP Conjugated antibody (bs-12194R-AP)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-12194R-AP
    英文名稱(chēng) Rabbit Anti-HOXB6/AP Conjugated antibody
    中文名稱(chēng) 堿性磷酸酶(AP)標記的同源盒蛋白B6抗體
    別    名 HGNC:5117; homeo box B6; Homeobox protein Hox B6; Hox-2.2; HOX2; HOX2B; HU-2; HXB6_HUMAN.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 腫瘤  細胞生物  發(fā)育生物學(xué)  轉錄調節因子  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Cow, )
    產(chǎn)品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 25kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from huuman HOXB6 (101-200aa)
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    HoxB6 is cytoplasmically expressed throughout fetal epidermal development, but displays nuclear expression in normal adult skin. HoxB6 protein also has nuclear expression in hyperproliferative skin conditions, but appears to be localized in the cytoplasm in basal and squamous cell carcinomas. HoxB6 genes are also expressed in normal adult lung.

    Function:
    HOXB6 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.

    Subcellular Location:
    Nuclear

    Post-translational modifications:
    Phosphorylated upon DNA damage, probably by ATM or ATR.

    Similarity:
    Belongs to the Antp homeobox family.
    Contains 1 homeobox DNA-binding domain.

    Database links:

    Entrez Gene: 3216 Human

    Entrez Gene: 15414 Mouse

    Entrez Gene: 497986 Rat

    Omim: 142961 Human

    SwissProt: P17509 Human

    SwissProt: P09023 Mouse

    Unigene: 98428 Human

    Unigene: 215 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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