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    Rabbit Anti-HBeAg/PE-Cy5.5 Conjugated antibody (bs-10386R-PE-Cy5.5)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-10386R-PE-Cy5.5
    英文名稱(chēng) Rabbit Anti-HBeAg/PE-Cy5.5 Conjugated antibody
    中文名稱(chēng) PE-Cy5.5標記的乙型肝炎e抗原抗體
    別    名 Hepatitis B Virus E Antigen; HBe antigen; HBeAg; HBVgp4; Pre C,C; Precore protein; Precore/core; Precore/core ORF; Precore/core protei; HBEAG_HBVD3; External core antigen; HBeAg; p25.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 細胞生物  免疫學(xué)  信號轉導  生長(cháng)因子和激素  轉錄調節因子  淋巴細胞  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應
    產(chǎn)品應用
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 12kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human HBeAg
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.

    Function:
    May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.

    Subunit:
    Homodimerizes.

    Subcellular Location:
    Secreted. Host nucleus.

    Post-translational modifications:
    Phosphorylated.
    Cleaved by host furin.

    Similarity:
    Belongs to the orthohepadnavirus precore antigen family.

    Database links:

    Entrez Gene: 944568 Hepatitis B virus

    SwissProt: Q89714 Hepatitis B virus




    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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