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    Rabbit Anti-CHST5/Gold Conjugated antibody (bs-13936R-Gold)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-13936R-Gold
    英文名稱(chēng) Rabbit Anti-CHST5/Gold Conjugated antibody
    中文名稱(chēng) 膠體金標記的碳水化合物磺基轉移酶5抗體
    別    名 Carbohydrate (N acetylglucosamine 6 O) sulfotransferase 5; Carbohydrate sulfotransferase 5; Chst5; CHST5_HUMAN; FLJ22167; Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 4 alpha; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha; GlcNAc6ST 3; GlcNAc6ST-3; Gn6st-3; GST4 alpha; GST4-alpha; Intestinal GlcNAc-6-sulfotransferase; N acetylglucosamine 6 O sulfotransferase 3.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
    研究領(lǐng)域 細胞生物  信號轉導  新陳代謝  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
    產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 46kDa
    性    狀 Lyophilized or Liquid
    濃    度 0.4mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CHST5
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
    保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
    產(chǎn)品介紹 background:
    The protein encoded by this gene belongs to the Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST) family, members of which catalyze the transfer of sulfate to position 6 of galactose (Gal), N-acetylgalactosamine (GalNAc), or N-acetylglucosamine (GlcNAc) residues within proteoglycans, and sulfation of O-linked sugars of mucin-type acceptors. Carbohydrate sulfation plays a critical role in many biologic processes. This gene is predominantly expressed in colon and small intestine. [provided by RefSeq, Aug 2011]

    Function:
    Catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of short carbohydrate substrates. However, it does not transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures. Has no activity toward keratan. Not involved in generating HEV-expressed ligands for L-selectin. Its substrate specificity may be influenced by its subcellular location.

    Subcellular Location:
    Golgi apparatus membrane. Golgi membrane, early secretory pathway.

    Tissue Specificity:
    Predominantly expressed in small and large intestines and colon. Weakly expressed in lymphocytes. Not expressed in other tissues. Down-regulated in colonic adenocarcinomas.

    Similarity:
    Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.

    Database links:
  • Entrez Gene: 23563 Human
  • Omim: 604817 Human
  • SwissProt: Q9GZS9 Human
  • Unigene: 156784 Human
  • Unigene: 710689 Human


  • Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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