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    Rabbit Anti-GABRG3/Cy5 Conjugated antibody (bs-12080R-Cy5)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-12080R-Cy5
    英文名稱(chēng) Rabbit Anti-GABRG3/Cy5 Conjugated antibody
    中文名稱(chēng) Cy5標記的G氨基丁酸受體γ3/GABAA Rγ3抗體
    別    名 GABA A Receptor gamma 3; GABA(A) receptor; GABA(A) receptor subunit gamma 3; GABR G3; GABRG 3; GABRG3; Gamma aminobutyric acid (GABA) A receptor gamma 3; Gamma aminobutyric acid A receptor gamma 3; Gamma aminobutyric acid receptor subunit gamma 3; GBRG3_HUMAN.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 神經(jīng)生物學(xué)  通道蛋白  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 Human,  (predicted: Mouse, Rat, )
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 52kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GABRG3/GABA A Receptor gamma 3
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]

    Function:
    GABA A Receptor gamma 3, is the ligand-gated ion channel that GABA A (gamma aminobutyric acid) exerts its inhibitory neurotransmitter funtion through.

    Subunit:
    Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.

    Subcellular Location:
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

    Post-translational modifications:
    May be palmitoylated

    Similarity:
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG3 sub-subfamily.

    Database links:

    Entrez Gene: 2567 Human

    Entrez Gene: 14407 Mouse

    Entrez Gene: 79211 Rat

    Omim: 600233 Human

    SwissProt: Q99928 Human

    SwissProt: P27681 Mouse

    SwissProt: P28473 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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