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    Rabbit Anti-GATAD1/PE-Cy3 Conjugated antibody (bs-11921R-PE-Cy3)
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    說(shuō) 明 書(shū): 100ul  
    100ul/2980.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-11921R-PE-Cy3
    英文名稱(chēng) Rabbit Anti-GATAD1/PE-Cy3 Conjugated antibody
    中文名稱(chēng) PE-Cy3標記的眼發(fā)育相關(guān)基因蛋白ODAG抗體
    別    名 ODAG; GATA zinc finger domain containing 1; Ocular development associated gene; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATAD1 protein; ocular development associated; ODAG; RG083M05.2; tcag7.279; GATD1_HUMAN.  
    規格價(jià)格 100ul/2980元 購買(mǎi)        大包裝/詢(xún)價(jià)
    說(shuō) 明 書(shū) 100ul  
    研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  信號轉導  生長(cháng)因子和激素  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
    產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 29kDa
    性    狀 Lyophilized or Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GATAD1/ODAG
    亞    型 IgG
    純化方法 affinity purified by Protein A
    儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    產(chǎn)品介紹 background:
    The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

    Function:
    ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue.

    Subunit:
    Component of a chromatin complex, at least composed of KDM5A, GATAD1 and EMSY.

    Subcellular Location:
    Nuclear

    Tissue Specificity:
    Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes.

    DISEASE:
    Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B) [MIM:614672]. CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

    Similarity:
    Contains 1 GATA-type zinc finger.

    Database links:

    Entrez Gene: 57798 Human

    Entrez Gene: 67210 Mouse

    SwissProt: Q8N5Y5 Human

    SwissProt: Q8WUU5 Human

    SwissProt: Q3TS14 Mouse

    SwissProt: Q8VCQ2 Mouse

    SwissProt: Q920S3 Mouse

    SwissProt: Q9CSG2 Mouse

    Unigene: 21145 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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