| 產(chǎn)品編號 | bsm-63304R |
| 英文名稱(chēng) | phospho-FGFR3 (Y642) Recombinant Rabbit mAb |
| 中文名稱(chēng) | 磷酸化成纖維細胞生長(cháng)因子受體3重組兔單抗 |
| 別 名 | ACH; CD333; CEK2; FGFR3; Fibroblast growth factor receptor 3; HSFGFR3EX; Hydroxyaryl protein kinase; JTK4; Tyrosine kinase JTK 4. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 克 隆 號 | 11G8 |
| 交叉反應 | Human,Mouse |
| 產(chǎn)品應用 | WB=1:1000-1:2000,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 88 kDa |
| 檢測分子量 | 88 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human FGFR3 around the phosphorylation site of Y642: DL-pY-MI |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. SWISS: P22607 Gene ID: 2261 成纖維細胞生長(cháng)因子受體3也是酪氨酸激酶受體家族成員，在細胞有絲分裂的發(fā)生、血管新生、傷口愈合及腫瘤形成中起重要作用。FGFR3目前多用于腫瘤方面的研究。 |
