| 產(chǎn)品編號 | bsm-63278R |
| 英文名稱(chēng) | phospho-Caveolin-1 (Y14) Recombinant Rabbit mAb |
| 中文名稱(chēng) | 磷酸化細胞質(zhì)膜微囊蛋白-1重組兔單抗 |
| 別 名 | BSCL3; CAV; CAV1; Caveolin1; CGL3; LCCNS; PPH3; VIP21. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 克 隆 號 | 2B5 |
| 交叉反應 | Human |
| 產(chǎn)品應用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 20 kDa |
| 檢測分子量 | 23 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Caveolin 1 around the phosphorylation site of Y14: EGHL-pY-TVPI |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. SWISS: Q03135 Gene ID: 857 信號傳導（Signaling Intermediates） Caveolin-1（小凹蛋白）是細胞生長(cháng)相關(guān)信號途徑及腫瘤發(fā)生發(fā)展過(guò)程中重要的抑制因子，Caveolae是細胞膜內的特殊膜結構，參與包括細胞的分子運輸、細胞粘附和信號轉導在內的多種細胞活動(dòng)。Caveolin-1是Caveolae中重要的結構蛋白，抑制細胞生長(cháng)，與多種人類(lèi)腫瘤發(fā)生發(fā)展相關(guān)的信號分子相互作用。Caveolin在信號轉導的整合中起支架蛋白的作用。Caveolin構成了一個(gè)蛋白家族，他們是細胞質(zhì)膜中發(fā)夾樣結構域的主要結構成分。Ca |
