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    DGKH Rabbit pAb (bs-25200R)  
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    產(chǎn)品編號 bs-25200R
    英文名稱(chēng) DGKH Rabbit pAb
    中文名稱(chēng) 甘油二酯激酶η/DGK-η抗體
    別    名 DAG kinase eta; DGK eta; DGKH_HUMAN; Diacylglycerol kinase eta; Diglyceride kinase eta.  
    研究領(lǐng)域 細胞生物  信號轉導  激酶和磷酸酶  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:400-800,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 135 kDa
    檢測分子量
    細胞定位 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DGKH: 741-840/1220 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a member of the diacylglycerol kinase (DGK) enzyme family of proteins, specifically the type II DGK subfamily. Members of this family are involved in regulating the intracellular concentrations of diacylglycerol and phosphatidic acid. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2011]

    Function:
    This gene encodes a member of the diacylglycerol kinase (DGK) enzyme family of proteins, specifically the type II DGK subfamily. Members of this family are involved in regulating the intracellular concentrations of diacylglycerol and phosphatidic acid. Two transcript variants encoding distinct isoforms have been identified for this gene.

    Subcellular Location:
    Cytoplasm. Translocated from the cytoplasm to endosomes in response to stress stimuli. Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal association.

    SWISS:
    Q86XP1

    Gene ID:
    160851

    Database links:

    Entrez Gene: 160851 Human

    Entrez Gene: 380921 Mouse

    Omim: 604071 Human

    SwissProt: Q86XP1 Human

    SwissProt: A0JP53 Mouse



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (human kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (DGKH) Polyclonal Antibody, Unconjugated (bs-25200R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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