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    SLC22A11 Rabbit pAb (bs-20723R)  
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    產(chǎn)品編號 bs-20723R
    英文名稱(chēng) SLC22A11 Rabbit pAb
    中文名稱(chēng) 有機陰離子轉運體4抗體
    別    名 hOAT4; MGC34282; OAT4; Organic anion transporter 4; Solute carrier family 22(organic anion/urate transporter) member 11; Solute carrier family 22 member 11; S22AB_HUMAN.  
    研究領(lǐng)域 腫瘤  信號轉導  生長(cháng)因子和激素  通道蛋白  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 60 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human SLC22A11: 21-120/550 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

    Function:
    Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.

    Subcellular Location:
    Cell membrane, Multi-pass membrane protein.

    Tissue Specificity:
    Detected in placenta and kidney.

    Post-translational modifications:
    N-glycosylated. Contains several complex-type N-glycans.

    Similarity:
    Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

    SWISS:
    Q9NSA0

    Gene ID:
    55867

    Database links:

    Entrez Gene: 55867 Human

    Omim: 607097 Human

    SwissProt: Q9NSA0 Human



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC22A11) Polyclonal Antibody, Unconjugated (bs-20723R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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