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    Prickle 2 Rabbit pAb (bs-19961R)  
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    產(chǎn)品編號 bs-19961R
    英文名稱(chēng) Prickle 2 Rabbit pAb
    中文名稱(chēng) 刺痛感蛋白2抗體
    別    名 PRIC2; PRIC2_HUMAN; prickle-like 2(Drosophila); prickle-like 2; Prickle-like protein 2; PRICKLE2.  
    研究領(lǐng)域 細胞生物  染色質(zhì)和核信號  干細胞  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Dog,Horse)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 96 kDa
    檢測分子量
    細胞定位 細胞核 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Prickle 2: 401-500/844 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011]

    Subcellular Location:
    Nucleus membrane.

    Tissue Specificity:
    Expressed in brain, eye and testis. Additionally in fetal brain, adult cartilage, pancreatic islet, gastric cancer and uterus tumors.

    DISEASE:
    Epilepsy, progressive myoclonic 5.

    Similarity:
    Belongs to the prickle / espinas / testin family.
    Contains 3 LIM zinc-binding domains.
    Contains 1 PET domain.

    SWISS:
    Q7Z3G6

    Gene ID:
    166336

    Database links:

    Entrez Gene: 166336 Human

    Entrez Gene: 243548 Mouse

    SwissProt: Q7Z3G6 Human

    SwissProt: Q80Y24 Mouse

    Unigene: 148105 Human

    Unigene: 699317 Human

    Unigene: 248820 Mouse



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Prickle 2) Polyclonal Antibody, Unconjugated (bs-19961R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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