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    NOL4 Rabbit pAb (bs-19310R)  
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    產(chǎn)品編號 bs-19310R
    英文名稱(chēng) NOL4 Rabbit pAb
    中文名稱(chēng) 核仁蛋白4抗體
    別    名 HRIHFB2255; NOL 4; NOL4; NOL4_HUMAN; NOLP; Nucleolar localized protein; Nucleolar protein 4; Nucleolar-localized protein.  
    研究領(lǐng)域 細胞生物  染色質(zhì)和核信號  神經(jīng)生物學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Dog)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 72 kDa
    檢測分子量
    細胞定位 細胞核 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NOL4: 1-100/638 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 NOL4 is a 524 amino acid protein that is predominantly expressed in testis and brain. NOL4 contains at least two domains that direct it to subnuclear locations. The gene encoding NOL4 is located on human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. There are two isoforms of NOL4 that are produced as a result of alternative splicing events.

    Subcellular Location:
    Nucleus > nucleolus.

    Tissue Specificity:
    Expressed predominantly in fetal brain, adult brain and testis.

    SWISS:
    O94818

    Gene ID:
    8715

    Database links:

    Entrez Gene: 8715 Human

    Omim: 603577 Human

    SwissProt: O94818 Human

    Unigene: 514795 Human



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NOL4) Polyclonal Antibody, Unconjugated (bs-19310R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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