| 產(chǎn)品編號 | bs-18867R |
| 英文名稱(chēng) | RSF1 Rabbit pAb |
| 中文名稱(chēng) | RSF1蛋白抗體 |
| 別 名 | HXBAP; p325; RSF1_HUMAN; remodeling and spacing factor 1; RSF 1; XAP8. |
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Specific References (1) | bs-18867R has been referenced in 1 publications.
[IF=4.982] Tian Jing. et al. linc00958/miR-185-5p/RSF-1 modulates cisplatin resistance and angiogenesis through AKT1/GSK3β/VEGFA pathway in cervical cancer. REPROD BIOL ENDOCRIN. 2022 Dec;20(1):1-12 IHC ; Mouse.
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| 研究領(lǐng)域 | 腫瘤 細胞生物 信號轉導 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 164 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RSF1: 31-130/1441 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a nuclear protein that interacts with hepatitis B virus X protein (HBX) and facilitates transcription of hepatitis B virus genes by the HBX transcription activator, suggesting a role for this interaction in the virus life cycle. This protein also interacts with SNF2H protein to form the RSF chromatin-remodeling complex, where the SNF2H subunit functions as the nucleosome-dependent ATPase, and this protein as the histone chaperone. [provided by RefSeq, Sep 2011] Function: Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Subunit: Interacts with SMARCA5/SNF2H to form the RSF complex. Also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome. Subcellular Location: Nucleus Tissue Specificity: Ubiquitously expressed. Similarity: Contains 1 DDT domain. Contains 1 PHD-type zinc finger. SWISS: Q96T23 Gene ID: 51773 Database links: Entrez Gene: 51773 Human Entrez Gene: 233532 Mouse Omim: 608522 Human SwissProt: Q96T23 Human Unigene: 420229 Human |
