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    ZCCHC24/C10orf56 Rabbit pAb (bs-18551R)  
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    產(chǎn)品編號 bs-18551R
    英文名稱(chēng) ZCCHC24/C10orf56 Rabbit pAb
    中文名稱(chēng) 10號染色體開(kāi)放閱讀框56抗體
    別    名 C10orf56; Chromosome 10 open reading frame 56; Zinc finger CCHC domain-containing protein 24; Zinc finger, CCHC domain containing 24.  
    研究領(lǐng)域 細胞生物  免疫學(xué)  鋅指蛋白  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Cow,Zebrafish,Chicken,Horse,Danio)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 27 kDa
    檢測分子量
    細胞定位 細胞核 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ZCCHC24/C10orf56: 101-200/241 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 ZCCHC24 is a 241 amino acid protein that contains one CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC24 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

    SWISS:
    Q8N2G6

    Gene ID:
    219654

    Database links:

    Entrez Gene: 219654 Human

    Entrez Gene: 71918 Mouse

    Entrez Gene: 361104 Rat

    SwissProt: Q8N2G6 Human

    SwissProt: B2RVL6 Mouse

    Unigene: 523080 Human

    Unigene: 41904 Mouse

    Unigene: 44060 Rat



    產(chǎn)品圖片
    Sample: Hela (human) Cell Lysate at 40 ug Primary: Anti-ZCCHC24/C10orf56 (bs-18551R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 27 kD Observed band size: 27 kD
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