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    ARFGAP2 Rabbit pAb (bs-18504R)  
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    產(chǎn)品編號 bs-18504R
    英文名稱(chēng) ARFGAP2 Rabbit pAb
    中文名稱(chēng) 鋅指蛋白289抗體
    別    名 ADP-ribosylation factor GTPase-activating protein 2; ARF GAP 2; ARFG2_HUMAN; FLJ14576; FLJ26000; GTPase activating protein ZNF289; GTPase-activating protein ZNF289; IRZ; Nbla10535; Zfp289; Zinc finger protein 289; Zinc finger protein 289 ID1 regulated; ZNF 289.  
    研究領(lǐng)域 轉錄調節因子  鋅指蛋白  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Horse)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 57 kDa
    檢測分子量
    細胞定位 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ZNF289/ARFGAP2: 401-500/521 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 ZNF289 functions as a GTPase-activating protein (GAP) for ARF family proteins. Localizing to the cytoplasmic side of the Golgi apparatus, ZNF289 contains one ARF-GAP domain and is found associated with COP-I-coated vesicles.

    Function:
    GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.

    Subunit:
    Interacts with the coatomer complex. Interacts with the C-terminal appendage domain of COPG1.

    Subcellular Location:
    Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note: Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.

    Similarity:
    Contains 1 Arf-GAP domain.

    SWISS:
    Q8N6H7

    Gene ID:
    84364

    Database links:

    Entrez Gene: 84364 Human

    Entrez Gene: 505438 Cow

    Entrez Gene: 77038 Mouse

    Entrez Gene: 362162 Rat

    Omim: 606908 Human

    SwissProt: A1L520 Cow

    SwissProt: Q8N6H7 Human

    SwissProt: Q99K28 Mouse

    SwissProt: Q3MID3 Rat

    Unigene: 436204 Human

    Unigene: 43636 Mouse

    Unigene: 3707 Rat



    產(chǎn)品圖片
    Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-ZNF289 (bs-18504R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD
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