| 產(chǎn)品編號 | bs-17704R |
| 英文名稱(chēng) | MOG1 Rabbit pAb |
| 中文名稱(chēng) | Ran結合蛋白MOG1抗體 |
| 別 名 | DKFZp686F02139; homolog of yeast MOG1; HSPC165; HSPC236; likely ortholog of mouse RAN guanine nucleotide release factor; MGC110973; MOG 1; MOG1; MOG1 homolog; MOG1_HUMAN; RAN guanine nucleotide release factor; Ran-binding protein MOG1; RANGNRF; RANGRF. |
| 研究領(lǐng)域 | 心血管 細胞生物 信號轉導 結合蛋白 G蛋白信號 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | Mouse,Rat (predicted: Human) |
| 產(chǎn)品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 20 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MOG1: 81-150/186 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] Function: May regulate the intracellular trafficking of RAN. In cardiac cells seems to regulate the cell surface localization of SCN5A. Subunit: Monomer (By similarity). Interacts with RAN, RAN-GTP and RAN-GDP. Forms a complex with RAN-GTP and RANBP1 (By similarity). Interacts with the cytoplasmic loop 2 of SCN5A. Subcellular Location: Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm. Tissue Specificity: Isoform 1 and isoform 2 are ubiquitously expressed. Similarity: Belongs to the MOG1 family. SWISS: Q9HD47 Gene ID: 29098 Database links: Entrez Gene: 29098 Human Entrez Gene: 57785 Mouse Omim: 607954 Human SwissProt: Q9HD47 Human SwissProt: Q9JIB0 Mouse Unigene: 408233 Human Unigene: 371612 Mouse |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOG1) Polyclonal Antibody, Unconjugated (bs-17704R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOG1) Polyclonal Antibody, Unconjugated (bs-17704R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MOG1) Polyclonal Antibody, Unconjugated (bs-17704R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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