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    MNF1 Rabbit pAb (bs-17693R)  
    訂購熱線(xiàn):400-901-9800
    訂購郵箱:sales@bioss.com.cn
    訂購QQ:  400-901-9800
    技術(shù)支持:techsupport@bioss.com.cn
    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-17693R
    英文名稱(chēng) MNF1 Rabbit pAb
    中文名稱(chēng) 線(xiàn)粒體類(lèi)核因子1/乳腺癌相關(guān)蛋白SGA-81M抗體
    別    名 bA6B20.2; Breast cancer-associated protein SGA-81M; C6orf125; Cbp6; UQCC2_HUMAN; M19; Mitochondrial nucleoid factor 1; Mitochondrial protein M19; MNF1; RP11-6B20.2.  
    研究領(lǐng)域 細胞生物  免疫學(xué)  新陳代謝  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human,Mouse,Rat,Sheep,Cow,Horse)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 13 kDa
    檢測分子量
    細胞定位 細胞漿 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human MNF1: 14-100/126 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008]

    Function:
    Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells.

    Subcellular Location:
    Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space (By similarity). Mitochondrion matrix (By similarity). Mitochondrion inner membrane (By similarity). Note=Predominantly expressed in the mitochondrial inner membrane (By similarity).

    Tissue Specificity:
    Pancreas, skeletal muscle, kidney, liver and heart.

    SWISS:
    Q9BRT2

    Gene ID:
    84300

    Database links:

    Entrez Gene: 84300 Human

    Omim: 614461 Human

    SwissProt: Q9BRT2 Human



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