| 產(chǎn)品編號 | bs-17278R |
| 英文名稱(chēng) | SCD5 Rabbit pAb |
| 中文名稱(chēng) | 硬脂酰輔酶A去飽和酶5抗體 |
| 別 名 | ACOD4; Acyl CoA desaturase 4; Acyl-CoA-desaturase 4; FADS4; FLJ21032; HSCD5; SCD2; SCD4; SCD5; SCD5_HUMAN; Stearoyl CoA 9 desaturase; stearoyl CoA desaturase 4; Stearoyl CoA desaturase 5; Stearoyl-CoA 9-desaturase; Stearoyl-CoA desaturase 5. |
| 研究領(lǐng)域 | 腫瘤 細胞生物 免疫學(xué) 信號轉導 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Human) |
| 產(chǎn)品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 38 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SCD5: 251-330/330 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008] Function: Fatty acid delta-9-desaturase that introduces a double bond in fatty acyl-coenzyme A at the delta-9 position. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Detected in fetal brain, and at lower levels in fetal kidney. Detected in adult brain and pancreas, and at lower levels in kidney and lung. Similarity: Belongs to the fatty acid desaturase family. SWISS: Q86SK9 Gene ID: 79966 Database links: Entrez Gene: 79966 Human Omim: 608370 Human SwissProt: Q86SK9 Human Unigene: 379191 Human |
