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    GPCR GPR87 Rabbit pAb (bs-16267R)  
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    產(chǎn)品編號 bs-16267R
    英文名稱(chēng) GPCR GPR87 Rabbit pAb
    中文名稱(chēng) G蛋白偶聯(lián)受體87抗體
    別    名 FKSG 78; FKSG78; G protein coupled receptor 87; G protein coupled receptor 95; G-protein coupled receptor 87; G-protein coupled receptor 95; GPCR87; GPR 87; GPR 95; GPR87; GPR87_HUMAN; GPR95; hGPCR87; KPG 002; KPG_002; MGC131898; Orphan GPCR 87; Probable G protein coupled receptor 87,  
    研究領(lǐng)域 腫瘤  信號轉導  G蛋白偶聯(lián)受體  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 41 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GPCR GPR87: 151-250/358 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011]

    Function:
    Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    Q9BY21

    Gene ID:
    53836

    Database links:

    Entrez Gene: 53836 Human

    Entrez Gene: 84111 Mouse

    Omim: 606379 Human

    SwissProt: Q9BY21 Human

    SwissProt: Q99MT7 Mouse

    Unigene: 591292 Human

    Unigene: 60267 Mouse



    產(chǎn)品圖片
    Sample: DU145(Human) Cell Lysate at 30 ug Primary: Anti-GPCR GPR87 (bs-16267R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 46 kD
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