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    ZBTB5 Rabbit pAb (bs-13581R)  
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    產(chǎn)品編號 bs-13581R
    英文名稱(chēng) ZBTB5 Rabbit pAb
    中文名稱(chēng) 鋅指蛋白ZBTB5抗體
    別    名 5930421I10; 9430083K24Rik; AI646847; Expressed in brain and neural tube; KIAA0354; mKIAA0354; OTTMUSP00000007812; OTTMUSP00000007813; OTTMUSP00000007814; RP11-397D12.5; RP23-218A4.2; Transcription factor ZNF POZ; Zbtb5; ZBTB5_HUMAN; Zinc finger and BTB domain containing protein 5; Zinc finger and BTB domain-containing protein 5.  
    研究領(lǐng)域 轉錄調節因子  鋅指蛋白  表觀(guān)遺傳學(xué)  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat,Rabbit,Sheep,Cow,Chicken,Dog,Horse)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 74 kDa
    檢測分子量
    細胞定位 細胞核 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ZBTB5: 581-677/677 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a 677 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB5 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB5 functions as a transcription regulator.

    Function:
    May be involved in transcriptional regulation.

    Subcellular Location:
    Nucleus.

    Similarity:
    Contains 1 BTB (POZ) domain.
    Contains 2 C2H2-type zinc fingers.

    SWISS:
    O15062

    Gene ID:
    9925

    Database links:

    Entrez Gene: 9925 Human

    Entrez Gene: 230119 Mouse

    Entrez Gene: 298084 Rat

    SwissProt: O15062 Human

    SwissProt: Q7TQG0 Mouse

    Unigene: 161276 Human



    產(chǎn)品圖片
    Sample:MCF-7 (Human)cell Lysate at 40 ug Primary: Anti-ZBTB5(bs-13581R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 74kD Observed band size: 75kD
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