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    GPR110 Rabbit pAb (bs-13513R)  
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    產(chǎn)品編號 bs-13513R
    英文名稱(chēng) GPR110 Rabbit pAb
    中文名稱(chēng) G蛋白偶聯(lián)受體110抗體
    別    名 G protein coupled receptor 110; G protein coupled receptor KPG_012; G protein coupled receptor PGR19; G-protein coupled receptor KPG_012; G-protein coupled receptor PGR19; GP110_HUMAN; GPR110; HGPCR36; KPG_012; PGR19; Probable G protein coupled receptor 110; Probable G-protein coupled receptor 110; GPCR GPR110.  
    Specific References  (1)     |     bs-13513R has been referenced in 1 publications.
    [IF=4.125] Minghui Zhang. et al. Comparative Transcriptomic Analysis of Mammary Gland Tissues Reveals the Critical Role of GPR110 in Palmitic Acid-Stimulated Milk Protein and Fat Synthesis. BRIT J NUTR. 2023 Mar;:1-32  WB ;  Mouse.  
    研究領(lǐng)域 細胞生物  神經(jīng)生物學(xué)  信號轉導  G蛋白偶聯(lián)受體  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human,Mouse
    產(chǎn)品應用 WB=1:500-2000,Flow-Cyt=1μg/Test
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 99 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human G protein coupled receptor 110: 51-150/910 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR110 (G protein-coupled receptor 110), also known as PGR19, is a 911 amino acid protein that belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Characterized as an adhesion GPCR, GPR110 is a multipass membrane-bound protein with a long amino-terminus that contains multiple domains. One of these domains is the GPCR proteolytic site (GPS), which is essential for proteolytic cleavage of the amino-terminus and for cell surface expression.

    Function:
    Orphan receptor.

    Subcellular Location:
    Cell membrane.

    Similarity:
    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
    Contains 1 SEA domain.

    SWISS:
    Q5T601

    Gene ID:
    266977

    Database links:

    Entrez Gene: 266977 Human

    SwissProt: Q5T601 Human

    Unigene: 733762 Human



    產(chǎn)品圖片
    Sample: A549 (human)Cell Lysate at 40 ug Primary: Anti-GPR110(bs-13513R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 99 kD Observed band size: 109 kD
    Sample: A431 (human)Cell Lysate at 40 ug Primary: Anti-GPR110(bs-13513R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 99 kD Observed band size: 109 kD
    Blank control(blue): Mouse Kidney Cells(fixed with 2% paraformaldehyde (10 min)). Primary Antibody:Rabbit Anti- GPR110 antibody(bs-13513R), Dilution: 1ug in 100 uL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
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