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    EGFL6 Rabbit pAb (bs-13062R)  
    訂購熱線(xiàn):400-901-9800
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    訂購QQ:  400-901-9800
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    50ul/1180.00元
    100ul/1980.00元
    200ul/2800.00元
    大包裝/詢(xún)價(jià)
    產(chǎn)品編號 bs-13062R
    英文名稱(chēng) EGFL6 Rabbit pAb
    中文名稱(chēng) 表皮生長(cháng)因子樣蛋白6抗體
    別    名 EGF like domain multiple 6; EGF repeat containing protein 6; EGF-like protein 6; EGF-like-domain multiple 6; egfl6; EGFL6_HUMAN; epidermal growth factor like protein 6; Epidermal growth factor-like protein 6; MAEG; MAM and EGF domain containing; MAM and EGF domains containing gene protein; MAM and EGF domains-containing gene protein; W80.  
    研究領(lǐng)域 腫瘤  細胞生物  神經(jīng)生物學(xué)  生長(cháng)因子和激素  細胞粘附分子  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 (predicted: Human,Mouse,Rat,Sheep,Cow,Dog,Horse)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 59 kDa
    檢測分子量
    細胞定位 細胞膜 細胞外基質(zhì) 分泌型蛋白 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human EGFL6: 231-330/553 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a member of the epidermal growth factor(EGF) repeat superfamily. Members of this superfamily arecharacterized by the presence of EGF-like repeats and are ofteninvolved in the regulation of cell cycle, proliferation, anddevelopmental processes. The gene product contains a signalpeptide, suggesting that it is secreted; an EGF repeat regionconsisting of 4 complete EGF-like repeats and 1 partial EGF-likerepeat, 3 of which have a calcium-binding consensus sequence; anarg-gly-asp integrin association motif; and a MAM domain, which isbelieved to have an adhesive function. This gene is expressed earlyduring development, and its expression has been detected in lungand meningioma tumors. [provided by RefSeq, Jul 2008].

    Function:
    May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.

    Subcellular Location:
    Secreted, extracellular space, extracellularmatrix, basement membrane (By similarity).

    Similarity:
    Belongs to the nephronectin family.
    Contains 5 EGF-like domains.
    Contains 1 MAM domain.

    SWISS:
    Q8IUX8

    Gene ID:
    25975

    Database links:

    Entrez Gene: 25975 Human

    Entrez Gene: 54156 Mouse

    Entrez Gene: 317470 Rat

    Omim: 300239 Human

    SwissProt: Q8IUX8 Human

    SwissProt: Q9JJZ5 Mouse



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