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    TAS2R5 Rabbit pAb (bs-11614R)  
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    產(chǎn)品編號 bs-11614R
    英文名稱(chēng) TAS2R5 Rabbit pAb
    中文名稱(chēng) 味覺(jué)受體蛋白家族2亞基5抗體
    別    名 T2R5; TA2R5_HUMAN; TAS2R5; Taste receptor T2R5; Taste receptor type 2 member 5; Taste receptor, type 2, member 5.  
    研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉導  通道蛋白  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 34 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TAS2R5: 51-150/299 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008].

    Function:
    Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

    Subcellular Location:
    Membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

    Similarity:
    Belongs to the G-protein coupled receptor T2R family.

    SWISS:
    Q9NYW4

    Gene ID:
    54429

    Database links:

    Entrez Gene: 54429 Human

    Omim: 605062 Human

    SwissProt: Q9NYW4 Human

    Unigene: 675370 Human



    產(chǎn)品圖片
    Sample: EC-9706(Human) Cell Lysate at 30 ug Primary: Anti-TAS2R5? (bs-11614R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 35 kD
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