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    FGFBP2 Rabbit pAb (bs-11284R)  
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    產(chǎn)品編號 bs-11284R
    英文名稱(chēng) FGFBP2 Rabbit pAb
    中文名稱(chēng) 纖維細胞生長(cháng)因子結合蛋白2抗體
    別    名 KSP37; FGF-binding protein 2; FGF-BP2; FGFBP-2; FGFBP2; FGFP2_HUMAN; Fibroblast growth factor-binding protein 2; HBp17-related protein; HBp17-RP; Ksp37; 37 kDa killer-specific secretory protein.  
    研究領(lǐng)域 免疫學(xué)  信號轉導  生長(cháng)因子和激素  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 23 kDa
    檢測分子量
    細胞定位 細胞外基質(zhì) 分泌型蛋白 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human FGFBP2/KSP37: 121-220/223 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 KSP37 is a 223 amino acid protein that is secreted into the extracellular space and belongs to the fibroblast growth factor-binding protein family. Expressed in serum, as well as in cytotoxic T lymphocytes and peripheral leukocytes, KSP37 is thought to be involved in lymphocyte-mediated immunity, possibly playing a role in the development of asthma. The gene encoding KSP37 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

    Subcellular Location:
    Secreted. extracellular space.

    Tissue Specificity:
    Expressed in serum, peripheral leukocytes and cytotoxic T lymphocytes, but not in granulocytes and monocytes (at protein level).

    Similarity:
    Belongs to the fibroblast growth factor-binding protein family.

    SWISS:
    Q9BYJ0

    Gene ID:
    83888

    Database links:

    Entrez Gene: 83888 Human

    Omim: 607713 Human

    SwissProt: Q9BYJ0 Human

    Unigene: 98785 Human



    產(chǎn)品圖片
    Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-FGFBP2 Polyclonal Antibody, Unconjugated(bs-R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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