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    PAR3 Rabbit pAb (bs-9510R)  
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    產(chǎn)品編號 bs-9510R
    英文名稱(chēng) PAR3 Rabbit pAb
    中文名稱(chēng) 蛋白酶激活受體3抗體
    別    名 Proteinase Activated Receptor 3; coagulation factor II(thrombin) receptor-like 2; Coagulation factor II receptor-like 2; F2RL2; PAR 3; PAR-3; PAR3; PAR3_HUMAN; protease activated receptor3; Proteinase-activated receptor 3; thrombin receptor like 2; Thrombin receptor-like 2.  
    Specific References  (2)     |     bs-9510R has been referenced in 2 publications.
    [IF=2.272] Liu et al. Effect of evodiamine and berberine on miR-429 as an oncogene in human colorectal cancer. (2016) Onco.Targets.Ther. 9:4121-7  WB ;  Human.  
    [IF=1.56] Huang, Chao, et al. "Analysis of different components in the peritumoral tissue microenvironment of colorectal cancer: A potential prospect in tumorigenesis. Corrigendum in/10.3892/mmr. 2016.5882." Molecular Medicine Reports 14.3 (2016): 2555-2565.  IHC-P ;  Human.  
    研究領(lǐng)域 心血管  細胞生物  信號轉導  G蛋白偶聯(lián)受體  G蛋白信號  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog)
    產(chǎn)品應用 WB=1:500-2000
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 42 kDa
    檢測分子量
    細胞定位 細胞膜 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human PAR3: 121-220/374 <Extracellular>
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
    Tissue specificity:
    Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

    Function:
    Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

    Post-translational modifications:
    A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    O00254

    Gene ID:
    2151

    Database links:

    Entrez Gene: 2151 Human

    Omim: 601919 Human

    SwissProt: Q58D85 Cow

    SwissProt: O00254 Human

    Unigene: 24447 Cow

    Unigene: 136948 Human

    Unigene: 42502 Human



    產(chǎn)品圖片
    Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- PAR3 (bs-9510R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 57 kD
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