| 產(chǎn)品編號 | bs-7836R |
| 英文名稱(chēng) | DCTN2 Rabbit pAb |
| 中文名稱(chēng) | 動(dòng)力蛋白激活蛋白2抗體 |
| 別 名 | 50 kD dynein associated polypeptide; 50 kDa dynein associated polypeptide; 50 kDa dynein-associated polypeptide; DCTN-50; DCTN2; DCTN2_HUMAN; DCTN50; dynactin 2(p50); dynactin 2; dynactin complex 50 kD subunit; Dynactin complex 50 kDa subunit; Dynactin subunit 2; p50 dynamitin; RBP50. |
| 研究領(lǐng)域 | 細胞生物 免疫學(xué) 信號轉導 細胞周期蛋白 細胞分化 細胞骨架 細胞外基質(zhì) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 44 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Dynamitin/DCTN2: 65-150/401 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. Function: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. Subunit: Subunit of dynactin, a multiprotein complex associated with dynein. Interacts with BICD2 and CEP135. Subcellular Location: Cytoplasm, cytoskeleton, centrosome. Membrane; Peripheral membrane protein. Similarity: Belongs to the dynactin subunit 2 family. SWISS: Q13561 Gene ID: 10540 Database links: UniProtKB/Swiss-Prot: Q13561.4 Entrez Gene: 10540 Human Entrez Gene: 69654 Mouse Omim: 607376 Human SwissProt: Q13561 Human SwissProt: Q99KJ8 Mouse Unigene: 289123 Human Unigene: 167537 Mouse |
| 產(chǎn)品圖片 |
Sample:
Spleen (Mouse) Lysate at 40 ug
Lung (Mouse) Lysate at 40 ug
Primary: Anti- DCTN2 (bs-7836R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 44 kD
Observed band size: 44 kD
Sample:
Bone (Mouse) Lysate at 40 ug
Primary: Anti- DCTN2 (bs-7836R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 44 kD
Observed band size: 44 kD
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