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    ITIH1 Rabbit pAb (bs-7018R)  
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    50ul/1180.00元
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    產(chǎn)品編號 bs-7018R
    英文名稱(chēng) ITIH1 Rabbit pAb
    中文名稱(chēng) 衍生透明質(zhì)酸相關(guān)蛋白抗體
    別    名 ITIH; H1P; Inter alpha trypsin inhibitor heavy chain H1; Inter-alpha-inhibitor heavy chain 1; Inter-alpha-trypsin inhibitor complex component III; Inter-alpha-trypsin inhibitor heavy chain H1; ITI heavy chain H1; ITI-HC1; ITIH1; ITIH1_HUMAN; Serum-derived hyaluronan-associated protein; SHAP.  
    研究領(lǐng)域 細胞生物  細胞表面分子  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat)
    產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 101 kDa
    檢測分子量
    細胞定位 分泌型蛋白 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human ITIH1: 195-290/911 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.

    Function:
    May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
    Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.

    Subunit:
    I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin.

    Subcellular Location:
    Secreted.

    Post-translational modifications:
    Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.
    The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal.

    Similarity:
    Belongs to the ITIH family.
    Contains 1 VIT domain.
    Contains 1 VWFA domain.

    SWISS:
    P19827

    Gene ID:
    3697

    Database links:

    Entrez Gene: 3697 Human

    Omim: 147270 Human

    SwissProt: P19827 Human

    Unigene: 420257 Human



    產(chǎn)品圖片
    Paraformaldehyde-fixed, paraffin embedded (human breast carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (ITIH1) Polyclonal Antibody, Unconjugated (bs-7018R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Paraformaldehyde-fixed, paraffin embedded (Human colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (ITIH1) Polyclonal Antibody, Unconjugated (bs-7018R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Paraformaldehyde-fixed, paraffin embedded (Human prostatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (ITIH1) Polyclonal Antibody, Unconjugated (bs-7018R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    Paraformaldehyde-fixed, paraffin embedded (human lung carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (ITIH1) Polyclonal Antibody, Unconjugated (bs-7018R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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