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    Galectin 7 Rabbit pAb (bs-5809R)  
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    50ul/1180.00元
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    200ul/2800.00元
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    產(chǎn)品編號 bs-5809R
    英文名稱(chēng) Galectin 7 Rabbit pAb
    中文名稱(chēng) 半乳糖凝集素7抗體
    別    名 Galectin7; Gal-7; GAL7; Galectin-7; HKL-14; Human keratinocyte lectin 14; Lectin galactoside binding soluble 7; LEG7_HUMAN; LGALS7; LGALS7B; p53-induced gene 1 protein; Pi7; PIG1; TP53I1.  
    研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  細胞凋亡  細胞粘附分子  細胞表面分子  
    抗體來(lái)源 Rabbit
    克隆類(lèi)型 Polyclonal
    克 隆 號
    交叉反應 Human (predicted: Mouse,Rat)
    產(chǎn)品應用 ICC/IF=1:50
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    理論分子量 15 kDa
    檢測分子量
    細胞定位 細胞核 細胞漿 分泌型蛋白 
    性    狀 Liquid
    濃    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Galectin 7.: 31-100/136 
    亞    型 IgG
    純化方法 affinity purified by Protein A
    緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    PubMed PubMed
    產(chǎn)品介紹 The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008].

    Function:
    Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

    Subunit:
    Monomer.

    Subcellular Location:
    Cytoplasm. Nucleus. Secreted (Potential). Note=May be secreted by a non-classical secretory pathway.

    Tissue Specificity:
    Mainly expressed in stratified squamous epithelium.

    Similarity:
    Contains 1 galectin domain.

    SWISS:
    P47929

    Gene ID:
    653499

    Database links:

    Entrez Gene: 3963 Human

    Entrez Gene: 653499 Human

    Entrez Gene: 16858 Mouse

    Entrez Gene: 29518 Rat

    Omim: 600615 Human

    SwissProt: P47929 Human

    SwissProt: O54974 Mouse

    SwissProt: P97590 Rat

    Unigene: 558355 Human

    Unigene: 707031 Human

    Unigene: 20973 Mouse

    Unigene: 6336 Rat



    產(chǎn)品圖片
    HUVEC cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (Galectin 7) polyclonal Antibody, Unconjugated (bs-5809R) 1:50, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
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