| 產(chǎn)品編號 | bs-1921R |
| 英文名稱(chēng) | TFF2 Rabbit pAb |
| 中文名稱(chēng) | 三葉肽因子2抗體 |
| 別 名 | TFF2_HUMAN; Trefoil factor 2; SML1; SP; Spasmolysin; Spasmolytic polypeptide(SP); |
| 研究領(lǐng)域 | 細胞生物 信號轉導 生長(cháng)因子和激素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | Mouse |
| 產(chǎn)品應用 | WB=1:200-1000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 12/14 kDa |
| 檢測分子量 | |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Recombinant Mouse TFF2 protein |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008] Function: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity). Subcellular Location: Secreted. Tissue Specificity: Stomach. Similarity: Contains 2 P-type (trefoil) domains. SWISS: Q03404 Gene ID: 21785 Database links: Entrez Gene: 7032 Human Entrez Gene: 21785 Mouse SwissProt: Q03403 Human SwissProt: Q03404 Mouse 三葉肽可能使黏膜凝膠產(chǎn)生更大的穩定性,使胃黏膜對各種損傷因子的防御能力增強。三葉肽在誘導上皮修復上的直接作用,可用于許多胃腸道疾病。它作為輔助劑或取代皮質(zhì)類(lèi)固醇或其他免疫抑制劑，在潰瘍病及炎癥性腸病的治療上可能是一個(gè)突破。 |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Small intestine tissue lysates
Lane 2: Mouse Pancreas tissue lysates
Primary: Anti-TFF2 (bs-1921R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 12-14 kDa
Observed band size: 15 kDa
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